Rat Model for Periodontitis (PD)

Pyorrhea; Periodontal Disease

FOR IN VITRO AND RESEARCH USE ONLY, NOT FOR USE IN CLINICAL DIAGNOSTIC PROCEDURES!
    • Product No.DSI547Ra02
    • Organism SpeciesRattus norvegicus (Rat)Same name, Different species.
    • Brand OwnerCLOUD-CLONE CORP.(CCC, USA)
    • ManufacturerCLOUD-CLONE CORP.(CCC, WUH)
    • Prototype SpeciesHuman
    • Sourceinduced by Neck ligation
    • Model Animal StrainsSPF Wistar rats, the teeth were intact, without caries and periodontal abnormalities, healthy, male,
    • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group.
    • Modeling Period6 weeks
    • Modeling Method1. rats were anesthetized with intraperitoneal injection of 10% chloral hydrate (350mg/kg).
      2. Dental probe separate first and second molar tooth gap, with the diameter of 0.2mm orthodontic stainless steel wire ligation of bilateral maxillary first molar tooth neck, with a needle holder holding a ligation wire into the rats from the bilateral maxillary first molars in the palatal, around the maxillary first molar after a week in the palatal side nearly at the fixed end of wire ligation, ligation of 3mm in subgingival retention back bend, prevent ligature scratch intraoral soft tissue, and no damage to the gingival junctional epithelium.
      3. Close observation the state of rats after fed sugar water from the day of the experiment, sugar diet (drinking water was 10% glucose water, feed 10% glucose water immersion becomes routine diet soft)every day. Observe the condition of periodontal tissue and the periodontal every week after surgery.
    • ApplicationsProvide an ideal animal model for the study of periodontitis
    • Downloadn/a
    • FormatEach case
    • FOBUS$ 100
      For negotiated price and more details, please contact local distributors!
    • Rat Model for Periodontitis (PD)Packages (Simulation)
    • Rat Model for Periodontitis (PD)Packages (Simulation)
    • DSI547Ra02.pngFig. ligatation of molar with orthodontic stainless steel wire
    • CertificateISO9001: 2008, ISO13485: 2003 Registered

    Model Evaluation

    Pathological Results

    Cytokines Level

    Statistical Analysis

    SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±s), using t test and single factor analysis of variance for group comparison, P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

    Related products

    Catalog No.Organism species: Rattus norvegicus (Rat)Applications
    DSI547Ra03Rat Model for Periodontitis (PD)n/a
    DSI547Ra02Rat Model for Periodontitis (PD)Provide an ideal animal model for the study of periodontitis
    DSI547Ra01Rat Model for Periodontitis (PD)n/a
    GUESTBOOK