Mouse Model for Melasma

Chloasma faciei; Yellow Speckle

  • Product No.DSI750Mu01
  • Organism SpeciesMus musculus (Mouse) Same name, Different species.
  • Prototype SpeciesHuman
  • SourceInduced by injection of progesterone combined with ultraviolet irradiation
  • Model Animal StrainsKunming (KM) mice, female, body weight: about 30g
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
  • Modeling Period6~8 weeks
  • Modeling Method10% sodium sulfide aqueous solution to remove the back of the mouse hair, naked skin area of 1.5cmx1.5cm. Daily intramuscular injection of 0.4% progesterone (5ml/Kg body weight);
    at the same time with a wavelength of 320nm in the ultraviolet (UVB) irradiation for a period of 6~8 weeks.
  • ApplicationsDisease Model
  • Download n/a
  • UOM Each case
  • FOB US$ 240
    For more details, please contact local distributors!
  • Mouse Model for Melasma Packages (Simulation)
  • Mouse Model for Melasma Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Model Evaluation of the Mouse Model for Melasma

1. The pathological morphology of skin melanocytes
2. MDA and SOD activity assay
3. Detection of behavior experiment:Open field test and Tail flick test

Pathological Results of the Mouse Model for Melasma

Cytokines Level of the Mouse Model for Melasma

Statistical Analysis of the Mouse Model for Melasma

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±s), using t test and single factor analysis of variance for group comparison, P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

Related products

Catalog No. Organism species: Mus musculus (Mouse) Applications (RESEARCH USE ONLY!)
DSI750Mu01 Mouse Model for Melasma Disease Model
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