Rat Model for Withdrawal Syndrome (WS)
Discontinuation syndrome
- Product No.DSI834Ra01
- Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
- Prototype SpeciesHuman
- SourceInduced by alcohol
- Model Animal StrainsSD rats (SPF class), Male, 6~8W, 200~250g
- Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
- Modeling Period4~8 weeks
- Modeling MethodThe rats were fed with 6% alcohol solution 28d, after withdrawal of alcohol observed the withdrawal syndrome .
- ApplicationsDisease Model
- Download n/a
- UOM Each case
-
FOB
US$ 180
For more details, please contact local distributors!
Model Evaluation of the Rat Model for Withdrawal Syndrome (WS)
Alcohol withdrawal after 24h, the rats were sacrificed, the brain, the content changes of cerebral cortex in p-CREB and BDNF were detected by QPCR method, the results show that the alcohol withdrawal 24h in the cerebral cortex p-CREB, BDNF decreased significantly.
Pathological Results of the Rat Model for Withdrawal Syndrome (WS)
Cytokines Level of the Rat Model for Withdrawal Syndrome (WS)
Statistical Analysis of the Rat Model for Withdrawal Syndrome (WS)
SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±s), using t test and single factor analysis of variance for group comparison, P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.
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Catalog No. | Organism species: Rattus norvegicus (Rat) | Applications (RESEARCH USE ONLY!) |
DSI834Ra01 | Rat Model for Withdrawal Syndrome (WS) | Disease Model |