Rat Model for Ocular Ischemic Syndrome (OIS)

  • Product No.DSI807Ra01
  • Organism SpeciesRattus norvegicus (Rat) Same name, Different species.
  • Prototype SpeciesHuman
  • SourceInduced by bilateral common carotid artery ligation
  • Model Animal StrainsBN rats (SPF), age: 3 months
  • Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
  • Modeling Period4~6 weeks
  • Modeling Method1. Rats were fasted before 8~12h, free drinking water. Intraperitoneal injection of 1% pentobarbital sodium 40mg/kg weight, lying on the back of the neck, make a 2~3cm incision, carefully separate the skin and muscles.
    2. Blunt dissection of the carotid artery in front of the neck muscle and lateral muscle gap and make a ligation of the carotid artery with a silk thread of 3-0. After suturing the skin from alcohol to disinfect the wound.
  • ApplicationsDisease Model
  • Download n/a
  • UOM Each case
  • FOB US$ 240
    For more details, please contact local distributors!
  • Rat Model for Ocular Ischemic Syndrome (OIS) Packages (Simulation)
  • Rat Model for Ocular Ischemic Syndrome (OIS) Packages (Simulation)
  • Certificate ISO9001: 2008, ISO13485: 2003 Registered

Model Evaluation of the Rat Model for Ocular Ischemic Syndrome (OIS)

1. Observe the pupillary light reflex in rats after modeling for 1 months;
2. One months after operation, the rats were examined by color fundus photography and fundus fluorescein angiography (FFA) examination of the fundus of the eye;
3. The rats were sacrificed to obtain the retina and the changes of retinal structure were detected by transmission electron microscope.

Pathological Results of the Rat Model for Ocular Ischemic Syndrome (OIS)

Cytokines Level of the Rat Model for Ocular Ischemic Syndrome (OIS)

Statistical Analysis of the Rat Model for Ocular Ischemic Syndrome (OIS)

SPSS software is used for statistical analysis, measurement data to mean ± standard deviation (x ±ｓ), using t test and single factor analysis of variance for group comparison, P<0.05 indicates there was a significant difference, P<0.01 indicates there are very significant differences.

Related products

Catalog No. Organism species: Rattus norvegicus (Rat) Applications (RESEARCH USE ONLY!)
DSI807Ra01 Rat Model for Ocular Ischemic Syndrome (OIS) Disease Model
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