Mouse Model for Uremia

Uraemia; Uremic poison; Uremic syndrome

• Urinary system

• Product No.DSI782Mu01
• Organism SpeciesMus musculus (Mouse) Same name, Different species.
• • All
  • Human
  • Mouse
  • Rat
  • Cavia
  • Rabbit
  • Simian
  • Caprine
  • Ovine
  • Equine
  • Bovine
  • Porcine
  • Gallus
  • Canine
  • Others
  • Multi-species
  • Pan-species
• Prototype SpeciesHuman
• SourceInduced by 5/6 nephrectomy
• Model Animal StrainsC56BL/6 mice (SPF class), Male, 6~8W, 22~25g
• Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group
• Modeling Period12 weeks
• Modeling Method1. 3% pentobarbital sodium solution (80mg/kg) intraperitoneal injection of mice;
  2. The left kidney was exposed to the left side of the abdominal incision, and the upper and lower poles of the left kidney (about 1/3 of the renal volume) were ligated respectively. Cut down the upper and lower pole at the same time, gelatin sponge compression hemostasis 2 mins, and layer by layer suture of peritoneum and skin;
  3. 1 weeks later, the same method was applied to exposed the right kidney, the right kidney was removed after ligation of the right renal artery and ureter.
• ApplicationsDisease Model
• Download n/a
• UOM Each case
• FOB US$ 280
  For more details, please contact local distributors!