Mouse Model for Myocardiosis

• Circulatory system

• Product No.DSI505Mu03
• Organism SpeciesMus musculus (Mouse) Same name, Different species.
• • All
  • Human
  • Mouse
  • Rat
  • Cavia
  • Rabbit
  • Simian
  • Caprine
  • Ovine
  • Equine
  • Bovine
  • Porcine
  • Gallus
  • Canine
  • Others
  • Multi-species
  • Pan-species
• Prototype SpeciesHuman
• SourceMyocarditis induced by diphtheria toxin
• Model Animal StrainsBalb/c Mice(SPF), healthy, male, age: 4~6weeks, body weight:18g~20g.
• Modeling GroupingRandomly divided into six group: Control group, Model group, Positive drug group and Test drug group(low,medium,high).
• Modeling Period4-6 weeks
• Modeling MethodUse the inbred mice with weight of 18 ~ 20g, age 4 ~ 6 weeks. The mice were intraperitoneally inoculated with 0.2ml of Coxsackie B3m virus (CVB3m, Nancy strain) to establish the severe Viral Myocarditis (VMC) model. Extract tissue samples after 1 week of inoculation. ①.Observe activity, food intake, body weight, coat color, and survival rate etc. ②.Observe the size, texture, color of the heart, liver and spleen. Weigh heart, liver and spleen / body weight (%) and thymus/body weight (%), heart/liver(%), heart/spleen(%), liver/spleen(%). ③.Pathological examination, take a piece of myocardial tissue, fix with 10% formaldehyde, conventional HE staining, observe the myocardial pathological changes.
• Applicationsn/a
• Download n/a
• UOM Each case
• FOB US$
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