Endomucin (EMCN)
EMCN2; MUC14; Endomucin-2; Gastric cancer antigen Ga34; Mucin-14
EMCN is a mucin-like sialoglycoprotein that interferes with the assembly of focal adhesion complexes and inhibits interaction between cells and the extracellular matrix .EMCN contains an N-terminal signal peptide, followed by a uteroglobin homology domain, a phosphatidylinositol 3-kinase RAS-binding domain, and a C-terminal transmembrane domain. The authors predicted that the N terminus is extracellular and the C terminus is intracellular. EMCN has several sites for N-glycosylation, N-myristoylation, and phosphorylation. Mouse and human EMCN share 49% amino acid homology. Northern blot analysis detected transcripts of 2.0 and 4.4 kb expressed at high levels in heart, kidney, and lung. Expression was minimal in peripheral blood leukocytes and could not be detected in several nonvascular cell lines.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Endomucin (EMCN) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Endomucin (EMCN) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Endomucin (EMCN) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Endomucin (EMCN) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Endomucin (EMCN) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Endomucin (EMCN) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Endomucin (EMCN) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Endomucin (EMCN) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Endomucin (EMCN) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Endomucin (EMCN) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Endomucin (EMCN) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Endomucin (EMCN) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Endomucin (EMCN) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Endomucin (EMCN) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Endomucin (EMCN) | ELISA Kit Customized Service Offer |