Receptor Interacting Serine Threonine Kinase 2 (RIPK2)
CCK; CARD3; CARDIAK; GIG30; RICK; RIP2; CARD-containing interleukin-1 beta-converting enzyme-associated kinase; Receptor-interacting 2; RIP-like-interacting CLARP kinase
Receptor-interacting serine/threonine-protein kinase 2 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase recruitment domain (CARD), and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of NF-kappa;B and inducer of apoptosis in response to various stimuli. Expression of RICK promoted the activation of caspase-8 and potentiated apoptosis induced by FAS, FADD, CLARP, and caspase-8. Northern blot analysis revealed that RICK is expressed in various human tissues as 2.5- and 1.8-kb mRNAs that differ due to alternative polyadenylation. The authors concluded that RICK is a novel kinase that may regulate apoptosis induced by the FAS receptor pathway.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB786Hu01 | Recombinant Receptor Interacting Serine Threonine Kinase 2 (RIPK2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB786Hu01 | Polyclonal Antibody to Receptor Interacting Serine Threonine Kinase 2 (RIPK2) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Receptor Interacting Serine Threonine Kinase 2 (RIPK2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Receptor Interacting Serine Threonine Kinase 2 (RIPK2) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB786Mu01 | Recombinant Receptor Interacting Serine Threonine Kinase 2 (RIPK2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB786Mu01 | Polyclonal Antibody to Receptor Interacting Serine Threonine Kinase 2 (RIPK2) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Receptor Interacting Serine Threonine Kinase 2 (RIPK2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Receptor Interacting Serine Threonine Kinase 2 (RIPK2) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB786Ra01 | Recombinant Receptor Interacting Serine Threonine Kinase 2 (RIPK2) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAB786Ra01 | Polyclonal Antibody to Receptor Interacting Serine Threonine Kinase 2 (RIPK2) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Receptor Interacting Serine Threonine Kinase 2 (RIPK2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Receptor Interacting Serine Threonine Kinase 2 (RIPK2) | ELISA Kit Customized Service Offer |