Osteoprotegerin (OPG)
TNFRSF11B; TNFRSF11-B; OCIF; OPG; TR1; Tumor Necrosis Factor Receptor Superfamily Member 11b; Osteoclastogenesis Inhibitory Factor
Osteoprotegerin (OPG) is a cytokine, which can inhibit the production of osteoclasts. It is a member of the tumor necrosis factor (TNF) receptor superfamily. It is a basic glycoprotein comprising 401 amino acid residues arranged into 7 structural domains. It is found as either a 60 kDa monomer or 120 kDa dimer linked by disulfide bonds.Osteoprotegerin inhibits the differentiation of osteoclast precursors into osteoclasts and also regulates the resorption of osteoclasts in vitro and in vivo. Osteoprotegerin is a RANK homolog, and works by binding to RANKL on osteoblast/stromal cells, thus blocking the RANKL-RANK ligand interaction between osteoblast/stromal cells and osteoclast precursors. This has the effect of inhibiting the differentiation of the osteoclast precursor into a mature osteoclast.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA108Hu01 | Recombinant Osteoprotegerin (OPG) | Positive Control; Immunogen; SDS-PAGE; WB. |
EPA108Hu61 | Eukaryotic Osteoprotegerin (OPG) | Positive Control; Immunogen; SDS-PAGE; WB. | |
APA108Hu01 | Active Osteoprotegerin (OPG) | Cell culture; Activity Assays. | |
RPA108Hu02 | Recombinant Osteoprotegerin (OPG) | Positive Control; Immunogen; SDS-PAGE; WB. | |
APA108Hu61 | Active Osteoprotegerin (OPG) | Cell culture; Activity Assays. | |
Antibodies | PAA108Hu01 | Polyclonal Antibody to Osteoprotegerin (OPG) | WB; IHC; ICC; IP. |
MAA108Hu22 | Monoclonal Antibody to Osteoprotegerin (OPG) | WB; IHC; ICC; IP. | |
PAA108Hu06 | Polyclonal Antibody to Osteoprotegerin (OPG) | WB; IHC; ICC; IP. | |
MAA108Hu21 | Monoclonal Antibody to Osteoprotegerin (OPG) | WB; IHC; ICC; IP. | |
MAA108Hu23 | Monoclonal Antibody to Osteoprotegerin (OPG) | WB; IHC; ICC; IP. | |
Assay Kits | SEA108Hu | ELISA Kit for Osteoprotegerin (OPG) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCA108Hu | CLIA Kit for Osteoprotegerin (OPG) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA108Mu01 | Recombinant Osteoprotegerin (OPG) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPA108Mu02 | Recombinant Osteoprotegerin (OPG) | Positive Control; Immunogen; SDS-PAGE; WB. | |
EPA108Mu61 | Eukaryotic Osteoprotegerin (OPG) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAA108Mu01 | Polyclonal Antibody to Osteoprotegerin (OPG) | WB; IHC; ICC; IP. |
PAA108Mu02 | Polyclonal Antibody to Osteoprotegerin (OPG) | WB; IHC; ICC; IP. | |
Assay Kits | SEA108Mu | ELISA Kit for Osteoprotegerin (OPG) | Enzyme-linked immunosorbent assay for Antigen Detection. |
SCA108Mu | CLIA Kit for Osteoprotegerin (OPG) | Chemiluminescent immunoassay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA108Ra01 | Recombinant Osteoprotegerin (OPG) | Positive Control; Immunogen; SDS-PAGE; WB. |
EPA108Ra61 | Eukaryotic Osteoprotegerin (OPG) | Positive Control; Immunogen; SDS-PAGE; WB. | |
EPA108Ra62 | Eukaryotic Osteoprotegerin (OPG) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAA108Ra01 | Polyclonal Antibody to Osteoprotegerin (OPG) | WB; IHC; ICC; IP. |
MAA108Ra21 | Monoclonal Antibody to Osteoprotegerin (OPG) | WB; IHC; ICC; IP. | |
Assay Kits | SEA108Ra | ELISA Kit for Osteoprotegerin (OPG) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Canis familiaris; Canine (Dog)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Osteoprotegerin (OPG) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Osteoprotegerin (OPG) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Osteoprotegerin (OPG) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEA108Ca | ELISA Kit for Osteoprotegerin (OPG) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Sus scrofa; Porcine (Pig)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA108Po01 | Recombinant Osteoprotegerin (OPG) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA108Po01 | Polyclonal Antibody to Osteoprotegerin (OPG) | WB; IHC; ICC; IP. |
MAA108Po21 | Monoclonal Antibody to Osteoprotegerin (OPG) | WB; IHC; ICC; IP. | |
Assay Kits | SEA108Po | ELISA Kit for Osteoprotegerin (OPG) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Capra hircus; Caprine (Goat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA108Cp01 | Recombinant Osteoprotegerin (OPG) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA108Cp01 | Polyclonal Antibody to Osteoprotegerin (OPG) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Osteoprotegerin (OPG) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Osteoprotegerin (OPG) | ELISA Kit Customized Service Offer |
Organism species: Chicken (Gallus)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA108Ga01 | Recombinant Osteoprotegerin (OPG) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA108Ga01 | Polyclonal Antibody to Osteoprotegerin (OPG) | WB; IHC; ICC; IP. |
MAA108Ga01 | Monoclonal Antibody to Osteoprotegerin (OPG) | WB; IHC; ICC; IP. | |
Assay Kits | SEA108Ga | ELISA Kit for Osteoprotegerin (OPG) | Enzyme-linked immunosorbent assay for Antigen Detection. |