Indoleamine-2,3-Dioxygenase (IDO)
CD107B; INDO; Indoleamine-Pyrrole 2,3 Dioxygenase
Indoleamine 2,3-dioxygenase (IDO) is an IFN-gamma inducible 42 kDa enzyme that catalyzes the degradation of the essential amino acid L-tryptophan to N-formylkynurenine. The gene encoding human IDO maps to chromosome 8p12-p11.
IDO, also known as INDO, is an important modulator of immunological responses and protects allogeneic concepti from alloreactive maternal lymphocytes. IDO mediates an interesting inhibitory effect of HeLa cells co-cultured with human PBLs. The ILN-2-induced proliferation response of PBLs is diminished in the presence of HeLa cells while an IDO inhbitor negates this effect. Flow cytometric analysis indicates both mature and immautre CD123-positive dentritic cells suppress T cell activity using IDO.
Organism species: Homo sapiens (Human)
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB547Mu01 | Recombinant Indoleamine-2,3-Dioxygenase (IDO) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB547Mu02 | Recombinant Indoleamine-2,3-Dioxygenase (IDO) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB547Mu01 | Polyclonal Antibody to Indoleamine-2,3-Dioxygenase (IDO) | WB; IHC; ICC; IP. |
PAB547Mu02 | Polyclonal Antibody to Indoleamine-2,3-Dioxygenase (IDO) | WB; IHC; ICC; IP. | |
Assay Kits | SEB547Mu | ELISA Kit for Indoleamine-2,3-Dioxygenase (IDO) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPB547Ra01 | Recombinant Indoleamine-2,3-Dioxygenase (IDO) | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB547Ra02 | Recombinant Indoleamine-2,3-Dioxygenase (IDO) | Positive Control; Immunogen; SDS-PAGE; WB. | |
Antibodies | PAB547Ra01 | Polyclonal Antibody to Indoleamine-2,3-Dioxygenase (IDO) | WB; IHC; ICC; IP. |
LAB547Ra71 | Biotin-Linked Polyclonal Antibody to Indoleamine-2,3-Dioxygenase (IDO) | WB; IHC; ICC. | |
MAB547Ra21 | Monoclonal Antibody to Indoleamine-2,3-Dioxygenase (IDO) | WB; IHC; ICC; IP. | |
PAB547Ra02 | Polyclonal Antibody to Indoleamine-2,3-Dioxygenase (IDO) | WB; IHC; ICC; IP. | |
Assay Kits | SEB547Ra | ELISA Kit for Indoleamine-2,3-Dioxygenase (IDO) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Oryctolagus cuniculus (Rabbit)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Indoleamine-2,3-Dioxygenase (IDO) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Indoleamine-2,3-Dioxygenase (IDO) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Indoleamine-2,3-Dioxygenase (IDO) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEB547Rb | ELISA Kit for Indoleamine-2,3-Dioxygenase (IDO) | Enzyme-linked immunosorbent assay for Antigen Detection. |