Hepatocyte Nuclear Factor 1 Alpha (HNF1a)
TCF1; HNF1; LFB1; LF-B1; MODY3; Transcription Factor 1,Hepatic; Hepatic Nuclear Factor; Albumin Proximal Factor; Liver-specific transcription factor LF-B1
HNF1a interacts with sequences required for optimal promoter function of the genes mentioned. The promoter or enhancer regions for several viral and cellular genes not expressed in the liver did not compete for binding to these sequences. HNF1 is predominantly expressed in liver and kidney.
HNF1 binds to the promoters of a variety of genes that are expressed exclusively in the liver, e.g., fibrinogen-alpha and -beta, albumin, alpha-fetoprotein, alpha-1-antitrypsin, liver-type pyruvate kinase, transthyretin, aldolase B, and hepatitis B virus large surface protein.HNF1-alpha, which displayed a restricted tissue distribution and did not bind to DNA but, rather, selectively stabilized HNF1-alpha dimers.
Organism species: Homo sapiens (Human)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPG775Hu01 | Recombinant Hepatocyte Nuclear Factor 1 Alpha (HNF1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAG775Hu01 | Polyclonal Antibody to Hepatocyte Nuclear Factor 1 Alpha (HNF1a) | WB; IHC; ICC; IP. |
| MAG775Hu21 | Monoclonal Antibody to Hepatocyte Nuclear Factor 1 Alpha (HNF1a) | WB; IHC; ICC; IP. | |
| Assay Kits | SEG775Hu | ELISA Kit for Hepatocyte Nuclear Factor 1 Alpha (HNF1a) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | RPG775Mu01 | Recombinant Hepatocyte Nuclear Factor 1 Alpha (HNF1a) | Positive Control; Immunogen; SDS-PAGE; WB. |
| Antibodies | PAG775Mu01 | Polyclonal Antibody to Hepatocyte Nuclear Factor 1 Alpha (HNF1a) | WB; IHC; ICC; IP. |
| PAG775Mu02 | Polyclonal Antibody to Hepatocyte Nuclear Factor 1 Alpha (HNF1a) | WB; IHC; ICC; IP. | |
| Assay Kits | SCG775Mu | CLIA Kit for Hepatocyte Nuclear Factor 1 Alpha (HNF1a) | Chemiluminescent immunoassay for Antigen Detection. |
| SEG775Mu | ELISA Kit for Hepatocyte Nuclear Factor 1 Alpha (HNF1a) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
| CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
| Proteins | n/a | Recombinant Hepatocyte Nuclear Factor 1 Alpha (HNF1a) | Recombinant Protein Customized Service Offer |
| Antibodies | n/a | Monoclonal Antibody to Hepatocyte Nuclear Factor 1 Alpha (HNF1a) | Monoclonal Antibody Customized Service Offer |
| n/a | Polyclonal Antibody to Hepatocyte Nuclear Factor 1 Alpha (HNF1a) | Polyclonal Antibody Customized Service Offer | |
| Assay Kits | n/a | CLIA Kit for Hepatocyte Nuclear Factor 1 Alpha (HNF1a) | CLIA Kit Customized Service Offer |
| n/a | ELISA Kit for Hepatocyte Nuclear Factor 1 Alpha (HNF1a) | ELISA Kit Customized Service Offer |