Growth Factor Receptor Bound Protein 2 (Grb2)
ASH; NCKAP2; EGFRBP-GRB2; Grb3-3; Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2
Growth factor receptor-bound protein 2 also known as Grb2 is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2 protein is encoded by the GRB2 gene.
The protein encoded by this gene binds receptors such as the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the sem-5 gene of Caenorhabditis elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
The protein encoded by this gene binds receptors such as the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the sem-5 gene of Caenorhabditis elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC514Hu01 | Recombinant Growth Factor Receptor Bound Protein 2 (Grb2) | Positive Control; Immunogen; SDS-PAGE; WB. |
EPC514Hu61 | Eukaryotic Growth Factor Receptor Bound Protein 2 (Grb2) | Positive Control; Immunogen; SDS-PAGE; WB. | |
APC514Hu61 | Active Growth Factor Receptor Bound Protein 2 (Grb2) | Cell culture; Activity Assays. | |
Antibodies | PAC514Hu01 | Polyclonal Antibody to Growth Factor Receptor Bound Protein 2 (Grb2) | WB; IHC; ICC; IP. |
MAC514Hu22 | Monoclonal Antibody to Growth Factor Receptor Bound Protein 2 (Grb2) | WB; IHC; ICC; IP. | |
PAC514Hu06 | Polyclonal Antibody to Growth Factor Receptor Bound Protein 2 (Grb2) | WB; IHC; ICC; IP. | |
Assay Kits | SEC514Hu | ELISA Kit for Growth Factor Receptor Bound Protein 2 (Grb2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Growth Factor Receptor Bound Protein 2 (Grb2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Growth Factor Receptor Bound Protein 2 (Grb2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Growth Factor Receptor Bound Protein 2 (Grb2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | SEC514Mu | ELISA Kit for Growth Factor Receptor Bound Protein 2 (Grb2) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Growth Factor Receptor Bound Protein 2 (Grb2) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Growth Factor Receptor Bound Protein 2 (Grb2) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Growth Factor Receptor Bound Protein 2 (Grb2) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Growth Factor Receptor Bound Protein 2 (Grb2) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Growth Factor Receptor Bound Protein 2 (Grb2) | ELISA Kit Customized Service Offer |