Dihydrolipoyl Dehydrogenase (DLD)
LAD; GCSL; Dihydrolipoamide Dehydrogenase; E3 Component Of Pyruvate Dehydrogenase Complex; 2-Oxo-Glutarate Complex; Branched Chain Keto Acid Dehydrogenase Complex
The dihydrolipoate, still bound to a lysine residue of the complex, then migrates to the dihydrolipoyl dehydrogenase (E3) active site where it undergoes a flavin-mediated oxidation, identical in chemistry to disulfide isomerase. First, FAD oxidizes dihydrolipoate back to its lipoate resting state, producing FADH2.
Dihydrolipoamide dehydrogenase is the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA919Hu01 | Recombinant Dihydrolipoyl Dehydrogenase (DLD) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA919Hu01 | Polyclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD) | WB; IHC; ICC; IP. |
MAA919Hu22 | Monoclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD) | WB; IHC; ICC; IP. | |
Assay Kits | n/a | CLIA Kit for Dihydrolipoyl Dehydrogenase (DLD) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Dihydrolipoyl Dehydrogenase (DLD) | ELISA Kit Customized Service Offer |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA919Mu01 | Recombinant Dihydrolipoyl Dehydrogenase (DLD) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA919Mu01 | Polyclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Dihydrolipoyl Dehydrogenase (DLD) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Dihydrolipoyl Dehydrogenase (DLD) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPA919Ra01 | Recombinant Dihydrolipoyl Dehydrogenase (DLD) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAA919Ra01 | Polyclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD) | WB; IHC; ICC; IP. |
Assay Kits | n/a | CLIA Kit for Dihydrolipoyl Dehydrogenase (DLD) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Dihydrolipoyl Dehydrogenase (DLD) | ELISA Kit Customized Service Offer |
Organism species: Canis familiaris; Canine (Dog)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Dihydrolipoyl Dehydrogenase (DLD) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Dihydrolipoyl Dehydrogenase (DLD) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Dihydrolipoyl Dehydrogenase (DLD) | ELISA Kit Customized Service Offer |