Dihydrolipoyl Dehydrogenase (DLD)

LAD; GCSL; Dihydrolipoamide Dehydrogenase; E3 Component Of Pyruvate Dehydrogenase Complex; 2-Oxo-Glutarate Complex; Branched Chain Keto Acid Dehydrogenase Complex

The dihydrolipoate, still bound to a lysine residue of the complex, then migrates to the dihydrolipoyl dehydrogenase (E3) active site where it undergoes a flavin-mediated oxidation, identical in chemistry to disulfide isomerase. First, FAD oxidizes dihydrolipoate back to its lipoate resting state, producing FADH2.

Dihydrolipoamide dehydrogenase is the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA919Hu01 Recombinant Dihydrolipoyl Dehydrogenase (DLD) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA919Hu01 Polyclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD) WB; IHC; ICC; IP.
MAA919Hu22 Monoclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Dihydrolipoyl Dehydrogenase (DLD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dihydrolipoyl Dehydrogenase (DLD) ELISA Kit Customized Service Offer

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA919Mu01 Recombinant Dihydrolipoyl Dehydrogenase (DLD) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA919Mu01 Polyclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Dihydrolipoyl Dehydrogenase (DLD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dihydrolipoyl Dehydrogenase (DLD) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPA919Ra01 Recombinant Dihydrolipoyl Dehydrogenase (DLD) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAA919Ra01 Polyclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD) WB; IHC; ICC; IP.
Assay Kits n/a CLIA Kit for Dihydrolipoyl Dehydrogenase (DLD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dihydrolipoyl Dehydrogenase (DLD) ELISA Kit Customized Service Offer

Organism species: Canis familiaris; Canine (Dog)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Dihydrolipoyl Dehydrogenase (DLD) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Dihydrolipoyl Dehydrogenase (DLD) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Dihydrolipoyl Dehydrogenase (DLD) CLIA Kit Customized Service Offer
n/a ELISA Kit for Dihydrolipoyl Dehydrogenase (DLD) ELISA Kit Customized Service Offer