Desmoplakin (DSP)
DPI; DPII; KPPS2; PPKS2; DP; 250/210 kDa paraneoplastic pemphigus antigen
Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques.
The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.
Organism species: Homo sapiens (Human)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | RPC203Hu01 | Recombinant Desmoplakin (DSP) | Positive Control; Immunogen; SDS-PAGE; WB. |
Antibodies | PAC203Hu01 | Polyclonal Antibody to Desmoplakin (DSP) | WB; IHC; ICC; IP. |
MAC203Hu22 | Monoclonal Antibody to Desmoplakin (DSP) | WB; IHC; ICC; IP. | |
MAC203Hu21 | Monoclonal Antibody to Desmoplakin (DSP) | WB; IHC; ICC; IP. | |
MAC203Hu23 | Monoclonal Antibody to Desmoplakin (DSP) | WB; IHC; ICC; IP. | |
Assay Kits | SEC203Hu | ELISA Kit for Desmoplakin (DSP) | Enzyme-linked immunosorbent assay for Antigen Detection. |
Organism species: Mus musculus (Mouse)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Desmoplakin (DSP) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Desmoplakin (DSP) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Desmoplakin (DSP) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Desmoplakin (DSP) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Desmoplakin (DSP) | ELISA Kit Customized Service Offer |
Organism species: Rattus norvegicus (Rat)
CATALOG NO. | PRODUCT NAME | APPLICATIONS | |
Proteins | n/a | Recombinant Desmoplakin (DSP) | Recombinant Protein Customized Service Offer |
Antibodies | n/a | Monoclonal Antibody to Desmoplakin (DSP) | Monoclonal Antibody Customized Service Offer |
n/a | Polyclonal Antibody to Desmoplakin (DSP) | Polyclonal Antibody Customized Service Offer | |
Assay Kits | n/a | CLIA Kit for Desmoplakin (DSP) | CLIA Kit Customized Service Offer |
n/a | ELISA Kit for Desmoplakin (DSP) | ELISA Kit Customized Service Offer |