Desmoplakin (DSP)

DPI; DPII; KPPS2; PPKS2; DP; 250/210 kDa paraneoplastic pemphigus antigen

Desmosomes are intercellular junctions that tightly link adjacent cells. Desmoplakin is an obligate component of functional desmosomes that anchors intermediate filaments to desmosomal plaques.
The N-terminus of desmoplakin is required for localization to the desmosome and interacts with the N-terminal region of plakophilin 1 and plakoglobin. The C-terminus of desmoplakin binds with intermediate filaments. In the mid-region of desmoplakin, a coiled-coiled rod domain is responsible for homodimerization. Mutations in this gene are the cause of several cardiomyopathies and keratodermas as well as the autoimmune disease paraneoplastic pemphigus.

Organism species: Homo sapiens (Human)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins RPC203Hu01 Recombinant Desmoplakin (DSP) Positive Control; Immunogen; SDS-PAGE; WB.
Antibodies PAC203Hu01 Polyclonal Antibody to Desmoplakin (DSP) WB; IHC; ICC; IP.
MAC203Hu22 Monoclonal Antibody to Desmoplakin (DSP) WB; IHC; ICC; IP.
MAC203Hu21 Monoclonal Antibody to Desmoplakin (DSP) WB; IHC; ICC; IP.
MAC203Hu23 Monoclonal Antibody to Desmoplakin (DSP) WB; IHC; ICC; IP.
Assay Kits SEC203Hu ELISA Kit for Desmoplakin (DSP) Enzyme-linked immunosorbent assay for Antigen Detection.

Organism species: Mus musculus (Mouse)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Desmoplakin (DSP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Desmoplakin (DSP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Desmoplakin (DSP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Desmoplakin (DSP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Desmoplakin (DSP) ELISA Kit Customized Service Offer

Organism species: Rattus norvegicus (Rat)

CATALOG NO. PRODUCT NAME APPLICATIONS
Proteins n/a Recombinant Desmoplakin (DSP) Recombinant Protein Customized Service Offer
Antibodies n/a Monoclonal Antibody to Desmoplakin (DSP) Monoclonal Antibody Customized Service Offer
n/a Polyclonal Antibody to Desmoplakin (DSP) Polyclonal Antibody Customized Service Offer
Assay Kits n/a CLIA Kit for Desmoplakin (DSP) CLIA Kit Customized Service Offer
n/a ELISA Kit for Desmoplakin (DSP) ELISA Kit Customized Service Offer